A41T (p.Ala41Thr) variant of IL6 (Interleukin-6)
A41T (p.Ala41Thr) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A41T (p.Ala41Thr) variant details
- p.Ala41Thr
- ExAC rs746818346
- TOPMed rs746818346
- gnomAD rs746818346
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.10
- MetaLR 0.10
- MetaSVM -0.93
- CADD 3.51
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 0.00017)
- Structural context available