A24T (p.Ala24Thr) variant of IL6 (Interleukin-6)
A24T (p.Ala24Thr) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A24T (p.Ala24Thr) variant details
- p.Ala24Thr
- TOPMed rs746848366
- gnomAD rs746848366
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.14
- MetaLR 0.08
- MetaSVM -0.95
- CADD 11.00
- SIFT 1.00
- Most common in the HGDP:XIBO population (allele frequency 0.056)
- Structural context available