A24S (p.Ala24Ser) variant of IL6 (Interleukin-6)
A24S (p.Ala24Ser) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A24S (p.Ala24Ser) variant details
- p.Ala24Ser
- TOPMed rs746848366
- gnomAD rs746848366
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.13
- MetaLR 0.13
- MetaSVM -1.03
- CADD 13.00
- PolyPhen-2 0.01
- SIFT 0.35
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available