A24P (p.Ala24Pro) variant of IL6 (Interleukin-6)
A24P (p.Ala24Pro) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
A24P (p.Ala24Pro) variant details
- p.Ala24Pro
- TOPMed rs746848366
- gnomAD rs746848366
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.32
- MetaLR 0.22
- MetaSVM -0.61
- CADD 19.40
- PolyPhen-2 0.30
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available