A13S (p.Ala13Ser) variant of IL6 (Interleukin-6)
A13S (p.Ala13Ser) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
A13S (p.Ala13Ser) variant details
- p.Ala13Ser
- ExAC rs767924065
- gnomAD rs767924065
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.29
- MetaLR 0.58
- MetaSVM 0.20
- CADD 25.50
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available