Y38S (p.Tyr38Ser) variant of IL4R (P24394)
Y38S (p.Tyr38Ser) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
Y38S (p.Tyr38Ser) variant details
- p.Tyr38Ser
- gnomAD 16-27342163-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.23
- MetaLR 0.21
- MetaSVM -0.91
- CADD 22.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available