W46* (p.Trp46Ter) variant of IL4R (P24394)
W46* (p.Trp46Ter) in IL4R (P24394) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
W46* (p.Trp46Ter) variant details
- p.Trp46Ter
- gnomAD 16-27341194-G-A
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.204
- CADD 8.38
- Most common in the Middle Eastern population (allele frequency 0.00025)
- Structural context available
- Literature evidence available