V28I (p.Val28Ile) variant of IL4R (P24394)
V28I (p.Val28Ile) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
V28I (p.Val28Ile) variant details
- p.Val28Ile
- gnomAD 16-27342132-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.07
- MetaLR 0.13
- MetaSVM -1.04
- CADD 18.80
- PolyPhen-2 0.96
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available