V20M (p.Val20Met) variant of IL4R (P24394)
V20M (p.Val20Met) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
V20M (p.Val20Met) variant details
- p.Val20Met
- TOPMed rs1191330149
- gnomAD rs1191330149
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.09
- CADD 24.50
- PolyPhen-2 0.64
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available