V20L (p.Val20Leu) variant of IL4R (P24394)
V20L (p.Val20Leu) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
V20L (p.Val20Leu) variant details
- p.Val20Leu
- TOPMed rs1191330149
- gnomAD rs1191330149
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.06
- CADD 20.80
- PolyPhen-2 0.08
- SIFT 0.08
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available