V16I (p.Val16Ile) variant of IL4R (P24394)
V16I (p.Val16Ile) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data, published literature, and structural context.
V16I (p.Val16Ile) variant details
- p.Val16Ile
- gnomAD 16-27340249-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0506
- REVEL 0.03
- CADD 0.74
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available