T43I (p.Thr43Ile) variant of IL4R (P24394)
T43I (p.Thr43Ile) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
T43I (p.Thr43Ile) variant details
- p.Thr43Ile
- cosmic curated COSV10503
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.17
- CADD 17.90
- PolyPhen-2 0.05
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available