S55I (p.Ser55Ile) variant of IL4R (P24394)
S55I (p.Ser55Ile) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
S55I (p.Ser55Ile) variant details
- p.Ser55Ile
- gnomAD 16-27342214-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.28
- MetaLR 0.19
- MetaSVM -0.91
- CADD 23.60
- PolyPhen-2 0.97
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available