S40N (p.Ser40Asn) variant of IL4R (P24394)
S40N (p.Ser40Asn) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
S40N (p.Ser40Asn) variant details
- p.Ser40Asn
- Ensembl rs2141133465
- Missense
- Variant Prioritization Score for Impact Estimate 0.0552
- REVEL 0.04
- CADD 2.60
- PolyPhen-2 0.33
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available