S22R (p.Ser22Arg) variant of IL4R (P24394)
S22R (p.Ser22Arg) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S22R (p.Ser22Arg) variant details
- p.Ser22Arg
- cosmic curated COSV99405
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.08
- CADD 21.70
- PolyPhen-2 0.09
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available