S22N (p.Ser22Asn) variant of IL4R (P24394)
S22N (p.Ser22Asn) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
S22N (p.Ser22Asn) variant details
- p.Ser22Asn
- gnomAD 16-27340268-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.04
- CADD 22.20
- PolyPhen-2 0.03
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available