P11S (p.Pro11Ser) variant of IL4R (P24394)
P11S (p.Pro11Ser) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
P11S (p.Pro11Ser) variant details
- p.Pro11Ser
- gnomAD 16-27340234-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.05
- CADD 10.80
- PolyPhen-2 0.01
- SIFT 0.29
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available