M39R (p.Met39Arg) variant of IL4R (P24394)
M39R (p.Met39Arg) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
M39R (p.Met39Arg) variant details
- p.Met39Arg
- gnomAD 16-27342166-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.24
- MetaLR 0.02
- MetaSVM -1.04
- CADD 16.00
- PolyPhen-2 0.01
- SIFT 0.35
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available