M26T (p.Met26Thr) variant of IL4R (P24394)
M26T (p.Met26Thr) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
M26T (p.Met26Thr) variant details
- p.Met26Thr
- gnomAD 16-27342127-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.04
- MetaLR 0.04
- MetaSVM -1.03
- CADD 15.30
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available