L9P (p.Leu9Pro) variant of IL4R (P24394)
L9P (p.Leu9Pro) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
L9P (p.Leu9Pro) variant details
- p.Leu9Pro
- ExAC rs771200748
- TOPMed rs771200748
- gnomAD rs771200748
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.19
- CADD 20.30
- PolyPhen-2 0.47
- SIFT 0.13
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available