L8I (p.Leu8Ile) variant of IL4R (P24394)
L8I (p.Leu8Ile) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
L8I (p.Leu8Ile) variant details
- p.Leu8Ile
- gnomAD 16-27340225-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.06
- CADD 16.60
- PolyPhen-2 0.65
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available