L8F (p.Leu8Phe) variant of IL4R (P24394)
L8F (p.Leu8Phe) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
L8F (p.Leu8Phe) variant details
- p.Leu8Phe
- gnomAD 16-27340225-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.03
- CADD 13.40
- PolyPhen-2 0.06
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available