L29S (p.Leu29Ser) variant of IL4R (P24394)
L29S (p.Leu29Ser) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L29S (p.Leu29Ser) variant details
- p.Leu29Ser
- gnomAD 16-27342136-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.22
- MetaLR 0.16
- MetaSVM -1.00
- CADD 21.40
- PolyPhen-2 0.96
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available