I41V (p.Ile41Val) variant of IL4R (P24394)
I41V (p.Ile41Val) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
I41V (p.Ile41Val) variant details
- p.Ile41Val
- gnomAD 16-27342171-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0619
- REVEL 0.01
- MetaLR 0.03
- MetaSVM -1.02
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available