G2W (p.Gly2Trp) variant of IL4R (P24394)
G2W (p.Gly2Trp) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
G2W (p.Gly2Trp) variant details
- p.Gly2Trp
- ExAC rs768492688
- gnomAD rs768492688
- Missense
- Variant Prioritization Score for Impact Estimate 0.517
- REVEL 0.31
- CADD 27.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available