G2R (p.Gly2Arg) variant of IL4R (P24394)
G2R (p.Gly2Arg) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
G2R (p.Gly2Arg) variant details
- p.Gly2Arg
- ExAC rs768492688
- gnomAD rs768492688
- Missense
- Variant Prioritization Score for Impact Estimate 0.499
- REVEL 0.29
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available