F10L (p.Phe10Leu) variant of IL4R (P24394)
F10L (p.Phe10Leu) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
F10L (p.Phe10Leu) variant details
- p.Phe10Leu
- ESP rs375986399
- ExAC rs375986399
- TOPMed rs375986399
- gnomAD rs375986399
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.03
- CADD 14.90
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available