E31A (p.Glu31Ala) variant of IL4R (P24394)
E31A (p.Glu31Ala) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
E31A (p.Glu31Ala) variant details
- p.Glu31Ala
- TOPMed rs908910299
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.12
- CADD 8.45
- PolyPhen-2 0.18
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available