D37N (p.Asp37Asn) variant of IL4R (P24394)
D37N (p.Asp37Asn) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
D37N (p.Asp37Asn) variant details
- p.Asp37Asn
- cosmic curated COSV50138
- ExAC rs776677335
- TOPMed rs776677335
- gnomAD rs776677335
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.17
- CADD 22.40
- PolyPhen-2 0.99
- SIFT 0.07
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available