C5R (p.Cys5Arg) variant of IL4R (P24394)
C5R (p.Cys5Arg) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
C5R (p.Cys5Arg) variant details
- p.Cys5Arg
- Ensembl rs914663466
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.11
- CADD 8.43
- PolyPhen-2 0.02
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available