C54Y (p.Cys54Tyr) variant of IL4R (P24394)
C54Y (p.Cys54Tyr) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
C54Y (p.Cys54Tyr) variant details
- p.Cys54Tyr
- gnomAD 16-27342211-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.608
- REVEL 0.57
- MetaLR 0.42
- MetaSVM -0.28
- CADD 24.20
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available