C34Y (p.Cys34Tyr) variant of IL4R (P24394)
C34Y (p.Cys34Tyr) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
C34Y (p.Cys34Tyr) variant details
- p.Cys34Tyr
- gnomAD 16-27342151-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.655
- REVEL 0.66
- MetaLR 0.43
- MetaSVM 0.06
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available