A21V (p.Ala21Val) variant of IL4R (P24394)
A21V (p.Ala21Val) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
A21V (p.Ala21Val) variant details
- p.Ala21Val
- gnomAD 16-27340265-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.06
- CADD 22.50
- PolyPhen-2 0.53
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available