A21T (p.Ala21Thr) variant of IL4R (P24394)
A21T (p.Ala21Thr) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
A21T (p.Ala21Thr) variant details
- p.Ala21Thr
- ESP rs150316902
- ExAC rs150316902
- TOPMed rs150316902
- gnomAD rs150316902
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.06
- CADD 13.70
- PolyPhen-2 0.16
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 0.00012)
- Structural context available