A21G (p.Ala21Gly) variant of IL4R (P24394)
A21G (p.Ala21Gly) in IL4R (P24394) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A21G (p.Ala21Gly) variant details
- p.Ala21Gly
- ExAC rs753306538
- gnomAD rs753306538
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.05
- CADD 22.00
- PolyPhen-2 0.68
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available