Y91C (p.Tyr91Cys) variant of IL2RG (P31785)
Y91C (p.Tyr91Cys) in IL2RG (P31785) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
Y91C (p.Tyr91Cys) variant details
- p.Tyr91Cys
- gnomAD rs1293196743
- Missense
- Variant Prioritization Score for Impact Estimate 0.662
- REVEL 0.73
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available