S168F (p.Ser168Phe) variant of IL2RG (P31785)
S168F (p.Ser168Phe) in IL2RG (P31785) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
S168F (p.Ser168Phe) variant details
- p.Ser168Phe
- TOPMed rs1382662571
- gnomAD rs1382662571
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.27
- CADD 18.60
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the South Asian population (allele frequency 7.4e-05)
- Structural context available