I111V (p.Ile111Val) variant of IL2RG (P31785)
I111V (p.Ile111Val) in IL2RG (P31785) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
I111V (p.Ile111Val) variant details
- p.Ile111Val
- TOPMed rs2092261466
- gnomAD rs2092261466
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.14
- CADD 4.48
- PolyPhen-2 0.00
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available