F41L (p.Phe41Leu) variant of IL2RG (P31785)
F41L (p.Phe41Leu) in IL2RG (P31785) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
F41L (p.Phe41Leu) variant details
- p.Phe41Leu
- TOPMed rs1160105152
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.28
- CADD 15.60
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available