W116C (p.Trp116Cys) variant of IL2RB (P14784)
W116C (p.Trp116Cys) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
W116C (p.Trp116Cys) variant details
- p.Trp116Cys
- ExAC rs773498163
- TOPMed rs773498163
- gnomAD rs773498163
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- REVEL 0.29
- CADD 23.10
- PolyPhen-2 0.78
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 0.00046)