T145I (p.Thr145Ile) variant of IL2RB (P14784)
T145I (p.Thr145Ile) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data.
T145I (p.Thr145Ile) variant details
- p.Thr145Ile
- gnomAD rs1216875084
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.18
- CADD 19.60
- PolyPhen-2 0.55
- SIFT 0.05
- Most common in the East Asian population (allele frequency 2.5e-05)