S58Y (p.Ser58Tyr) variant of IL2RB (P14784)
S58Y (p.Ser58Tyr) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data.
S58Y (p.Ser58Tyr) variant details
- p.Ser58Tyr
- TOPMed rs1922069074
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.51
- CADD 21.90
- PolyPhen-2 0.80
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)