R111C (p.Arg111Cys) variant of IL2RB (P14784)
R111C (p.Arg111Cys) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data.
R111C (p.Arg111Cys) variant details
- p.Arg111Cys
- ESP rs369774326
- ExAC rs369774326
- TOPMed rs369774326
- gnomAD rs369774326
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.50
- CADD 18.00
- PolyPhen-2 0.68
- SIFT 0.18
- Most common in the REMAINING population (allele frequency 1.7e-05)