P18T (p.Pro18Thr) variant of IL2RB (P14784)
P18T (p.Pro18Thr) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data.
P18T (p.Pro18Thr) variant details
- p.Pro18Thr
- TOPMed rs1001259966
- gnomAD rs1001259966
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.35
- CADD 0.21
- PolyPhen-2 0.09
- SIFT 0.20
- Most common in the Latino/Admixed American population (allele frequency 5.6e-05)