N43S (p.Asn43Ser) variant of IL2RB (P14784)
N43S (p.Asn43Ser) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data.
N43S (p.Asn43Ser) variant details
- p.Asn43Ser
- ExAC rs756309404
- TOPMed rs756309404
- gnomAD rs756309404
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- REVEL 0.35
- CADD 25.00
- PolyPhen-2 0.89
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)