L6M (p.Leu6Met) variant of IL2RB (P14784)
L6M (p.Leu6Met) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
L6M (p.Leu6Met) variant details
- p.Leu6Met
- TOPMed rs973200850
- gnomAD rs973200850
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.27
- CADD 15.40
- PolyPhen-2 0.95
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.8e-05)