L13F (p.Leu13Phe) variant of IL2RB (P14784)
L13F (p.Leu13Phe) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data.
L13F (p.Leu13Phe) variant details
- p.Leu13Phe
- TOPMed rs1402969708
- gnomAD rs1402969708
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.39
- CADD 23.30
- PolyPhen-2 0.71
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3.2e-05)