L132P (p.Leu132Pro) variant of IL2RB (P14784)
L132P (p.Leu132Pro) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data.
L132P (p.Leu132Pro) variant details
- p.Leu132Pro
- TOPMed rs1221462854
- gnomAD rs1221462854
- Missense
- Variant Prioritization Score for Impact Estimate 0.591
- REVEL 0.73
- CADD 26.50
- PolyPhen-2 0.96
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 4.8e-05)