H146R (p.His146Arg) variant of IL2RB (P14784)
H146R (p.His146Arg) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data.
H146R (p.His146Arg) variant details
- p.His146Arg
- TOPMed rs1244275084
- gnomAD rs1244275084
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.20
- CADD 3.00
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the African/African-American population (allele frequency 2.4e-05)