F124L (p.Phe124Leu) variant of IL2RB (P14784)
F124L (p.Phe124Leu) in IL2RB (P14784) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data.
F124L (p.Phe124Leu) variant details
- p.Phe124Leu
- TOPMed rs1321097046
- gnomAD rs1321097046
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.10
- CADD 21.80
- PolyPhen-2 0.02
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 2.4e-05)